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Ovarian Cancer Trial Results
6. Review Confirms Effectiveness of Intraperitoneal Chemotherapy for Advanced Ovarian Cancer
(Posted: 12/18/2006) - Combined data from 60 randomized clinical trials of advanced ovarian cancer showed that multidrug chemotherapy using a platinum-based drug and a taxane-based drug delivered directly into the abdomen (intraperitoneal chemotherapy) can help women survive a median of 5.5 years, according to the Nov. 15, 2006, Journal of the National Cancer Institute.
7. Preventive Surgery Can Reduce Cancer Risk in Women with BRCA Gene Mutations
(Posted: 05/28/2002, Updated: 10/04/2006) - Two separate studies in the May 23, 2002, issue of the New England Journal of Medicine support the practice of recommending preventive surgery in women with a genetic mutation that puts them at high risk of developing breast and gynecologic cancers.
8. Gemcitabine Plus Carboplatin Benefits Women with Recurrent Ovarian Cancer
(Posted: 09/27/2006) - A phase III randomized trial has shown a statistically significant improvement in progression-free survival for women with platinum-sensitive recurrent ovarian cancer given gemcitabine with carboplatin compared with carboplatin alone, according to a report published online Sept. 18, 2006, by the Journal of Clinical Oncology.
9. NCI Issues Clinical Announcement for Preferred Method of Treatment for Advanced Ovarian Cancer
(Posted: 01/04/2006) - NCI today issued an announcement encouraging treatment with anticancer drugs via two methods, after surgery, for women with advanced ovarian cancer. The combined methods, which deliver drugs into a vein and directly into the abdomen, extend overall survival for women with advanced ovarian cancer by about a year.
Questions and Answers
10. Ovarian Cancer Screening Using Ultrasound and CA125 Finds both Early and Late Stage Cancers, But Also Many False Positives
(Posted: 11/07/2005) - A new study from the NCI shows that currently available screening methods such as transvaginal ultrasound and testing for a protein biomarker called CA-125, alone or in combination, can detect ovarian cancer but can also produce many false-positive test results, causing needless surgery. Questions and Answers
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